Task Force Opening: Shared Molecular Etiologies Underlying Multiple Rare Diseases

The Interdisciplinary Scientific Committee (ISC) is establishing a Task Force on Shared Molecular Etiologies Underlying Multiple Rare Diseases aiming to address and document the existing challenges in adapting the basket trial approach used in molecularly targeted oncology clinical trials to drugs targeting shared molecular etiologies underlying multiple rare diseases. The Task Force will identify how previous, ongoing, and planned activities address these challenges and provide recommendations to potential funders on how they might help accelerate this process, and thereby greatly expand the number of rare disease patients in clinical trials.

The ISC is looking for members to populate this Task Force with the below expertise in one or more of the following areas:

  • Clinician/Scientist
  • Methodologist
  • Expert in Clinical Trial Design
  • Regulators, Rare Disease Policy
  • Patient Advocates
  • Research Funders

The usual time commitment includes quarterly 1-hour teleconferences, one face-to-face workshop (1-2 days), and regular email correspondence.

If you are interested in taking part in this activity, please send a CV, biosketch and letter of motivation (one paragraph each) to the Scientific Secretariat, scisec-irdirc(a)ejprarediseases.org before March 1st, 2021.

Importantly, do not forget to add in the subject of your email the reference of the project (Ref: TF-ISC-SaME).

Only selected candidates will be contacted. Other applications will be kept for potential future use.

The Interdisciplinary Scientific Committee (ISC) is establishing a Task Force on Shared Molecular Etiologies Underlying Multiple Rare Diseases aiming to address and document the existing challenges in adapting the basket trial approach used in molecularly targeted oncology clinical trials to drugs targeting shared molecular etiologies underlying multiple rare diseases. The Task Force will identify how previous, ongoing, and planned activities address these challenges and provide recommendations to potential funders on how they might help accelerate this process, and thereby greatly expand the number of rare disease patients in clinical trials.

The ISC is looking for members to populate this Task Force with the below expertise in one or more of the following areas:

  • Clinician/Scientist
  • Methodologist
  • Expert in Clinical Trial Design
  • Regulators, Rare Disease Policy
  • Patient Advocates
  • Research Funders

The usual time commitment includes quarterly 1-hour teleconferences, one face-to-face workshop (1-2 days), and regular email correspondence.

If you are interested in taking part in this activity, please send a CV, biosketch and letter of motivation (one paragraph each) to the Scientific Secretariat, scisec-irdirc(a)ejprarediseases.org before March 1st, 2021.

Importantly, do not forget to add in the subject of your email the reference of the project (Ref: TF-ISC-SaME).

Only selected candidates will be contacted. Other applications will be kept for potential future use.