The Operating Committee consists of the Chair and Vice Chair of the Consortium Assembly, the Chairs or Vice Chairs of the Constituent and Scientific Committees, and the Scientific Secretariat.
The Operating Committee meets regularly to prepare and advance IRDiRC activities, process information, and enable more effective management of the consortium as a whole.
| Name | Function within IRDiRC | Title and Organization | |
|---|---|---|---|
 | David Pearce | Chair Consortium Assembly | President of Innovation, Research & World Clinic Sanford Health, USA |
 | Samantha Parker | Vice Chair Consortium Assembly | Chief Patient Access Officer, Innoskel, France |
 | Christopher McMaster | Chair Funders Constituent Committee | Scientific Director, Canadian Institutes for Health Research (CIHR), Canada |
 | Stefano Benvenuti | Vice Chair Funders Constituent Committee | Head of Public Affairs, Telethon Foundation, Italy |
 | Vinciane Pirard | Chair Companies Constituent Committee | Lead Scientific Advocacy and Insights - Global Medical Affairs Rare Diseases |
 | Adriana Huertas-Vazquez | Vice Chair Companies Constituent Committee | Senior Director, Global Medical Affairs |
 | Durhane Wong-Rieger | Chair Patient Advocates Constituent Committee | Chair of the RDI Council, Global |
 | Samuel Agyei Wiafe | Vice Chair Patient Advocates Constituent Committee | Founder/Executive Director Rare Disease Ghana Initiative (RDGI), Ghana |
 | David Adams | Chair Diagnostics Scientific Committee | Deputy Director of Clinical Genomics, Office of the Clinical Director/ NHGRI, MGB/NHGRI, UDP/NIH, USA |
 | Clara van Karnebeek | Vice Chair Diagnostics Scientific Committee | Principal Investigator and Medical Director, Amsterdam UMC, The Netherlands |
 | Gareth Baynam | Chair Interdisciplinary Scientific Committee | Medical Director at Rare Care Centre, Perth Children’s Hospital, Australia |
 | Marc Dooms | Vice Chair Interdisciplinary Scientific Committee | Center for Clinical Pharmacology, University Hospitals Leuven, Belgium |
 | Daniel O'Connor | Chair Therapies Scientific Committee | Director, Regulatory Policy and Early Access, The Association of the British Pharmaceutical Industry (ABPI), UK |
 | Anneliene Jonker | Vice Chair Therapies Scientific Committee | Program Lead Personalised Medicine, University of Twente, The Netherlands |
 | Anne Pariser | Chair Regulatory Scientific Committee | VP, Medical and Regulatory Affairs at Alltrna, USA |
 | Violeta Stoyanova-Beninska | Vice Chair Regulatory Scientific Committee | Chair of Committee for Orphan Medicinal Products, EMA, The Netherlands |