Sanford Research, USA

2018

• Aberrant mitochondrial redox regulation in Friedreich’s Ataxia (website)

2017

• Understanding the impact of gut microbiota on the nuerological phenotypes and pathology in mouse models of childhood neurodegenerative diseases (website)

2016

• Molecular and Cellular Mechanisms of Choroid Plexus Tumor (website)
• Redox signaling in bronchopulmonary dysplasia (website)

2015

• Improving Merkel Cell Carcinoma Treatment Options (website)
• Improving treatment for Epstein Barr Virus (EBV) induced cancer (website)
• Improving treatment for HPV6b/11 induced disorders (website)
• Mechanisms underlying neural phenotypes of cholesterol synthesis disorders (website)
• Molecular Pathogenesis and biology of osteosarcoma (website)
• Role on Nonmuscle Myosin II in membrane trafficking and organ function (website)
• The Role of Notch Pathway in Bone Development and Osteosarcoma (website)

2014

• Multifaceted preclinical studies for the treatment of Batten Disease (website)
• Neurofibromatosis type 1 Disease Model (website)

2013

• Behavioral and pathological characterization of novel mouse models of the fatal neurodegenerative disorders, infantile, late infantile, juvenile Batten diseases (website)
• The molecular regulators of kidney collecting duct differentiation (website)

2012

• Pig models for Ataxia telangiectasia and Batten disease (website)

2011

• Cellular and molecular mechanisms by which aberrant Notch signaling causes cystic kidney disease (website)
• Investigating the mechanisms of disease for the nuclear laminopathies (website)

2010

• Coordination of Rare Diseases at Sanford (CoRDS) (website)
• CRMP2/CLN6/KLC4: Mechanisms that mediate cargo selection and transport in developing & mature axons in Batten disease (website)
• Genetic Causes of Primary Ciliary Dyskinesia (website)
• Genetic Susceptibility of Congenital Hydrocephalus (website)
• Redox signaling in bronchopulmonary dysplasia (website)
• Study of the molecular mechanisms of medulloblastoma initiation and progression (website)
• Testing various pharmacotherapeutic approaches in mouse models of infantile, late infantile, and juvenile Batten diseases (website)