IRDiRC has three Constituent Committees:
- Companies Constituent Committee (CCC)
- Funders Constituent Committee (FCC)
- Patient Advocates Constituent Committee (PACC)
Each Constituent Committee is composed of IRDiRC members who are identified as part of that constituency (e.g., industry-based IRDiRC members participate in the Companies Constituent Committee). The Constituent Committees act as coordinating bodies of each respective constituent space, inform the Consortium Assembly of scientific and programmatic needs following identification of common roadblocks, gaps and priorities, and execute activities specific to their constituency space that will bring IRDiRC closer to its goals. The Chair and the Vice Chair of each Constituent Committee are elected for a period of 3 years that can be renewed once.